help  | about  | cite  | software

Gene : SELENOI Homo sapiens

Name  ? selenoprotein I Cytological Location  2p23.3
Brief Description  selenoprotein I
description  The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]
  • synonyms:
  • SELI,
  • HGNC:29361,
  • EPT1,
  • uc021veu.2,
  • EPT1,
  • SEPI,
  • SELENOI,
  • SELI,
  • ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific),
  • OTTHUMG00000151931,
  • ethanolaminephosphotransferase 1,
  • SEPI,
  • KIAA1724,
  • NM_033505.2
  • identifiers:
  • 85465,
  • ENSG00000138018,
  • SELENOI

Genome feature

Region: gene ? Length: 49806  
Location: 2:26346086-26395891 Cyto location: 2p23.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

310 SN Ps

5 Cross References

15 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results