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Gene : RUNX3 Homo sapiens

Name  ? RUNX family transcription factor 3 Cytological Location  1p36.11
Brief Description  runt related transcription factor 3
description  This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  • synonyms:
  • NM_004350,
  • HGNC:10473,
  • CBFA3,
  • AML2,
  • AML2,
  • PEBP2aC,
  • uc001bjq.4,
  • OTTHUMG00000003316,
  • runt related transcription factor 3,
  • CBFA3,
  • BC013362,
  • runt-related transcription factor 3,
  • PEBP2A3,
  • RUNX3
  • identifiers:
  • 864,
  • ENSG00000020633,
  • RUNX3

Genome feature

Region: gene ? Length: 65648  
Location: 1:24899511-24965158 reverse strand Cyto location: 1p36.11

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

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35 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results