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Gene : ADAM18 Homo sapiens

Name  ? ADAM metallopeptidase domain 18 Cytological Location  8p11.22
Brief Description  ADAM metallopeptidase domain 18
description  This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature sperm surface protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
  • synonyms:
  • AJ133004,
  • OTTHUMG00000164040,
  • ADAM27,
  • NM_014237,
  • uc003xni.4,
  • ADAM27,
  • ADAM18,
  • tMDCIII,
  • a disintegrin and metalloproteinase domain 18,
  • HGNC:196,
  • tMDCIII
  • identifiers:
  • 8749,
  • ENSG00000168619,
  • ADAM18

Genome feature

Region: gene ? Length: 145497  
Location: 8:39584568-39730064 Cyto location: 8p11.22


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

129 SN Ps

3 Cross References

12 Data Sets

29 Homologues

0 Located Features

90 Rna Seq Results