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Gene : ADAM15 Homo sapiens

Name  ? ADAM metallopeptidase domain 15 Cytological Location  1q21.3
Brief Description  ADAM metallopeptidase domain 15
description  The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000013898,
  • MDC15,
  • HGNC:193,
  • NM_003815,
  • U46005,
  • uc001fgr.3,
  • ADAM15,
  • metargidin,
  • MDC15,
  • a disintegrin and metalloproteinase domain 15 (metargidin)
  • identifiers:
  • 8751,
  • ENSG00000143537,
  • ADAM15

Genome feature

Region: gene ? Length: 11505  
Location: 1:155051272-155062776 Cyto location: 1q21.3


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Disease

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Expression

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657 SN Ps

5 Cross References

17 Data Sets

28 Homologues

0 Located Features

90 Rna Seq Results