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Gene : SOCS3 Homo sapiens

Name  ? suppressor of cytokine signaling 3 Cytological Location  17q25.3
Brief Description  suppressor of cytokine signaling 3
description  This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
  • synonyms:
  • SOCS3,
  • SSI-3,
  • SOCS-3,
  • SSI-3,
  • CIS3,
  • SOCS-3,
  • uc002jvl.4,
  • Cish3,
  • Cish3,
  • HGNC:19391,
  • AB004904,
  • SSI3,
  • CIS3,
  • OTTHUMG00000177513,
  • NM_003955,
  • ATOD4
  • identifiers:
  • 9021,
  • ENSG00000184557,
  • SOCS3

Genome feature

Region: gene ? Length: 3303  
Location: 17:78356777-78360079 reverse strand Cyto location: 17q25.3

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0 Diseases

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5 SN Ps

5 Cross References

16 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results