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Gene : ACVR2A Homo sapiens

Name  ? activin A receptor type 2A Cytological Location  2q22.3-q23.1
Brief Description  activin A receptor type 2A
description  This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
  • synonyms:
  • ACVR2,
  • ACVR2A,
  • ACTRII,
  • HGNC:173,
  • ACVR2,
  • uc002twh.5,
  • OTTHUMG00000150603,
  • ACTRII,
  • activin A receptor, type IIA,
  • activin A receptor, type II,
  • NM_001616
  • identifiers:
  • 92,
  • ENSG00000121989,
  • ACVR2A

Genome feature

Region: gene ? Length: 86311  
Location: 2:147844517-147930827 Cyto location: 2q22.3-q23.1


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Disease

0 Diseases

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Expression

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2011 SN Ps

5 Cross References

17 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results