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Gene : AIMP1 Homo sapiens

Name  ? aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Cytological Location  4q24
Brief Description  aminoacyl tRNA synthetase complex interacting multifunctional protein 1
description  The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]
  • synonyms:
  • U10117,
  • uc011cfg.3,
  • p43,
  • EMAPII,
  • SCYE1,
  • ARS-interacting multifunctional protein 1,
  • EMAPII,
  • AIMP1,
  • EMAP II,
  • EMAP2,
  • EMAP-2,
  • SCYE1,
  • p43,
  • small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating),
  • HLD3,
  • NM_004757,
  • HGNC:10648,
  • OTTHUMG00000131217
  • identifiers:
  • 9255,
  • ENSG00000164022,
  • AIMP1

Genome feature

Region: gene ? Length: 33616  
Location: 4:106315610-106349225 Cyto location: 4q24


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Disease

1 Diseases

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Expression

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Other

527 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results