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Gene : AKAP5 Homo sapiens

Name  ? A-kinase anchoring protein 5 Cytological Location  14q23.3
Brief Description  A-kinase anchoring protein 5
description  The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000029634,
  • HGNC:375,
  • NM_004857,
  • uc001xhd.4,
  • AKAP75,
  • M90359,
  • AKAP79,
  • AKAP5,
  • AKAP79,
  • AKAP75,
  • A kinase (PRKA) anchor protein 5,
  • H21
  • identifiers:
  • 9495,
  • ENSG00000179841,
  • AKAP5

Genome feature

Region: gene ? Length: 9005  
Location: 14:64465499-64474503 Cyto location: 14q23.3


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

17 SN Ps

5 Cross References

15 Data Sets

2 Homologues

0 Located Features

90 Rna Seq Results