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Gene : ADAMTS3 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 3 Cytological Location  4q13.3
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 3
description  This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
  • synonyms:
  • NM_014243,
  • ADAMTS3,
  • AB002364,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3,
  • ADAMTS-4,
  • HGNC:219,
  • uc003hgk.2,
  • KIAA0366,
  • ADAMTS-4,
  • HKLLS3,
  • OTTHUMG00000129912
  • identifiers:
  • 9508,
  • ENSG00000156140,
  • ADAMTS3

Genome feature

Region: gene ? Length: 287831  
Location: 4:72280969-72568799 reverse strand Cyto location: 4q13.3


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

617 SN Ps

4 Cross References

16 Data Sets

31 Homologues

0 Located Features

90 Rna Seq Results