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Gene : ADAMTS1 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 1 Cytological Location  21q21.3
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 1
description  This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:217,
  • METH1,
  • OTTHUMG00000078688,
  • NM_006988,
  • AF060152,
  • METH1,
  • ADAMTS1,
  • C3-C5,
  • C3-C5,
  • KIAA1346,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1,
  • uc002ymf.4
  • identifiers:
  • 9510,
  • ENSG00000154734,
  • ADAMTS1

Genome feature

Region: gene ? Length: 9123  
Location: 21:26836287-26845409 reverse strand Cyto location: 21q21.3


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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

20 SN Ps

5 Cross References

15 Data Sets

34 Homologues

0 Located Features

90 Rna Seq Results