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Gene : TMEM59 Homo sapiens

Name  ? transmembrane protein 59 Cytological Location  1p32.3
Brief Description  transmembrane protein 59
description  This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
  • synonyms:
  • DCF1,
  • HSPC001,
  • TMEM59,
  • PRO195,
  • chromosome 1 open reading frame 8,
  • C1orf8,
  • UNQ169,
  • AF047439,
  • HGNC:1239,
  • uc001cwp.4,
  • HSPC001,
  • C1orf8,
  • OTTHUMG00000008437,
  • NM_004872
  • identifiers:
  • 9528,
  • ENSG00000116209,
  • TMEM59

Genome feature

Region: gene ? Length: 26893  
Location: 1:54026681-54053573 reverse strand Cyto location: 1p32.3

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

897 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

90 Rna Seq Results