help  | about  | cite  | software

Gene : ADGRE5 Homo sapiens

Name  ? adhesion G protein-coupled receptor E5 Cytological Location  19p13.12
Brief Description  adhesion G protein-coupled receptor E5
description  This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
  • synonyms:
  • CD97 molecule,
  • CD97,
  • seven-transmembrane, heterodimeric receptor associated with inflammation,
  • leukocyte antigen CD97,
  • seven transmembrane helix receptor,
  • ADGRE5,
  • seven-span transmembrane protein,
  • HGNC:1711,
  • NM_078481,
  • CD97,
  • TM7LN1,
  • TM7LN1,
  • OTTHUMG00000182166,
  • CD97 antigen
  • identifiers:
  • 976,
  • ENSG00000123146,
  • ADGRE5

Genome feature

Region: gene ? Length: 27582  
Location: 19:14381144-14408725 Cyto location: 19p13.12


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

76 SN Ps

4 Cross References

15 Data Sets

27 Homologues

0 Located Features

90 Rna Seq Results