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Gene : SEPTIN7 Homo sapiens

Name  ? septin 7 Cytological Location  7p14.2
Brief Description  septin 7
description  This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]
  • synonyms:
  • OTTHUMG00000155063,
  • SEPT7A,
  • HGNC:1717,
  • S72008,
  • NBLA02942,
  • CDC10 cell division cycle 10 homolog (S. cerevisiae),
  • SEPT7,
  • CDC10,
  • SEPT7,
  • CDC3,
  • CDC3,
  • SEPT7A,
  • NM_001788,
  • CDC10,
  • uc064ctx.2,
  • SEPT7
  • identifiers:
  • 989,
  • ENSG00000122545,
  • SEPTIN7

Genome feature

Region: gene ? Length: 114778  
Location: 7:35800986-35915763 Cyto location: 7p14.2


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Disease

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Other

480 SN Ps

5 Cross References

16 Data Sets

25 Homologues

0 Located Features

90 Rna Seq Results