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Gene : HLA-DQA2 Homo sapiens

Name  ? major histocompatibility complex, class II, DQ alpha 2 Cytological Location  6p21.32
Brief Description  major histocompatibility complex, class II, DQ alpha 2
description  This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]
  • synonyms:
  • OTTHUMG00000031108,
  • uc011hzy.3,
  • HLA-DXA,
  • HLA-DXA,
  • DC-alpha,
  • DX-ALPHA,
  • HLA-DCA,
  • HGNC:4943,
  • HLA-DQA2,
  • HLADQA2,
  • NM_020056
  • identifiers:
  • 3118,
  • ENSG00000237541,
  • HLA-DQA2

Genome feature

Region: gene ? Length: 5502  
Location: 6:32741386-32746887 Cyto location: 6p21.32


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

145004 SN Ps

4 Cross References

13 Data Sets

25 Homologues

0 Located Features

90 Rna Seq Results