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Gene : CHST8 Homo sapiens

Name  ? carbohydrate sulfotransferase 8 Cytological Location  19q13.11
Brief Description  carbohydrate sulfotransferase 8
description  The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • synonyms:
  • AB047801,
  • GalNAc4ST,
  • NM_022467,
  • OTTHUMG00000180472,
  • CHST8,
  • carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8,
  • GALNAC4ST1,
  • uc002nus.5,
  • GALNAC-4-ST1,
  • PSS3,
  • HGNC:15993
  • identifiers:
  • 64377,
  • ENSG00000124302,
  • CHST8

Genome feature

Region: gene ? Length: 151555  
Location: 19:33621955-33773509 Cyto location: 19q13.11


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Disease

1 Diseases

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742 SN Ps

5 Cross References

18 Data Sets

12 Homologues

0 Located Features

90 Rna Seq Results