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Gene : PTPN2 Homo sapiens

Name  ? protein tyrosine phosphatase non-receptor type 2 Cytological Location  18p11.21
Brief Description  protein tyrosine phosphatase, non-receptor type 2
description  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
  • synonyms:
  • PTPN2,
  • TC-PTP,
  • NM_080422,
  • TCPTP,
  • M25393,
  • NM_080423,
  • HGNC:9650,
  • TCPTP,
  • PTPT,
  • TC-PTP,
  • PTN2,
  • PTPT,
  • NM_002828,
  • uc002krp.4,
  • OTTHUMG00000131702
  • identifiers:
  • 5771,
  • ENSG00000175354,
  • PTPN2

Genome feature

Region: gene ? Length: 98874  
Location: 18:12785478-12884351 reverse strand Cyto location: 18p11.21

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0 Diseases

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130 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results