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Gene : DBI Homo sapiens

Name  ? diazepam binding inhibitor, acyl-CoA binding protein Cytological Location  2q14.2
Brief Description  diazepam binding inhibitor, acyl-CoA binding protein
description  This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • endozepine,
  • EP,
  • ACBD1,
  • HGNC:2690,
  • DBI,
  • ACBP,
  • uc002tlx.5,
  • CCK-RP,
  • NM_020548,
  • L76366,
  • ACBD1,
  • diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein),
  • ACBP,
  • OTTHUMG00000131403
  • identifiers:
  • 1622,
  • ENSG00000155368,
  • DBI

Genome feature

Region: gene ? Length: 5628  
Location: 2:119366924-119372551 Cyto location: 2q14.2


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Disease

0 Diseases

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Other

577 SN Ps

5 Cross References

16 Data Sets

11 Homologues

0 Located Features

90 Rna Seq Results