help  | about  | cite  | software

Gene : MRTFA Homo sapiens

Name  ? myocardin related transcription factor A Cytological Location  22q13.1-q13.2
Brief Description  megakaryoblastic leukemia (translocation) 1
description  The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • uc032qph.2,
  • MKL1,
  • HGNC:14334,
  • BSAC,
  • MAL,
  • MKL1,
  • MKL,
  • KIAA1438,
  • MAL,
  • megakaryocytic acute leukemia,
  • NM_020831,
  • OTTHUMG00000151146,
  • BSAC,
  • MKL1,
  • MKL,
  • MRTF-A,
  • megakaryoblastic leukemia (translocation) 1,
  • AB037859,
  • basic, SAP and coiled-coil domain,
  • MRTF-A
  • identifiers:
  • 57591,
  • ENSG00000196588,
  • MRTFA

Genome feature

Region: gene ? Length: 226582  
Location: 22:40410281-40636862 reverse strand Cyto location: 22q13.1-q13.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

441 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results