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Gene : ADAMTS7 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 7 Cytological Location  15q25.1
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 7
description  The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]
  • synonyms:
  • DKFZp434H204,
  • ADAMTS7,
  • ADAM-TS7,
  • AF140675,
  • NM_014272,
  • uc002bej.4,
  • HGNC:223,
  • COMPase,
  • ADAM-TS 7,
  • ADAMTS-7,
  • ADAM-TS7,
  • a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein,
  • OTTHUMG00000172907,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
  • identifiers:
  • 11173,
  • ENSG00000136378,
  • ADAMTS7

Genome feature

Region: gene ? Length: 52274  
Location: 15:78759203-78811476 reverse strand Cyto location: 15q25.1


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Proteins

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Expression

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2011 SN Ps

4 Cross References

14 Data Sets

29 Homologues

0 Located Features

90 Rna Seq Results