help  | about  | cite  | software

Gene : LPA Homo sapiens

Name  ? lipoprotein(a) Cytological Location  6q25.3-q26
Brief Description  lipoprotein(a)
description  The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]
  • synonyms:
  • LP,
  • uc063sqy.1,
  • X06290,
  • NM_005577,
  • AK38,
  • APOA,
  • LPA,
  • OTTHUMG00000015956,
  • HGNC:6667,
  • Lp(a),
  • LP,
  • apolipoprotein(a),
  • lipoprotein, Lp(a)
  • identifiers:
  • 4018,
  • ENSG00000198670,
  • LPA

Genome feature

Region: gene ? Length: 134893  
Location: 6:160531483-160666375 reverse strand Cyto location: 6q25.3-q26


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

175 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results