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Gene : AARS Homo sapiens

Name  ? alanyl-tRNA synthetase Cytological Location  16q22.1
Brief Description  alanyl-tRNA synthetase
description  The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]
  • synonyms:
  • EIEE29,
  • alanine tRNA ligase 1, cytoplasmic,
  • CMT2N,
  • uc002eyn.2,
  • NM_001605,
  • HGNC:20,
  • D32050,
  • AARS,
  • OTTHUMG00000177042,
  • AlaRS,
  • CMT2N
  • identifiers:
  • 16,
  • ENSG00000090861,
  • AARS

Genome feature

Region: gene ? Length: 37215  
Location: 16:70252295-70289509 reverse strand Cyto location: 16q22.1


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

945 SN Ps

5 Cross References

19 Data Sets

9 Homologues

0 Located Features

90 Rna Seq Results