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Gene : GNB1L Homo sapiens

Name  ? G protein subunit beta 1 like Cytological Location  22q11.21
Brief Description  G protein subunit beta 1 like
description  This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc002zqf.2,
  • OTTHUMG00000150279,
  • AF238328,
  • guanine nucleotide binding protein (G protein), beta polypeptide 1-like,
  • NM_053004,
  • GY2,
  • DGCRK3,
  • FKSG1,
  • WDR14,
  • GY2,
  • HGNC:4397,
  • WDVCF,
  • WDR14,
  • GNB1L
  • identifiers:
  • 54584,
  • ENSG00000185838,
  • GNB1L

Genome feature

Region: gene ? Length: 66529  
Location: 22:19788411-19854939 reverse strand Cyto location: 22q11.21


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0 Pathways

353 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results