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Gene : MVP Homo sapiens

Name  ? major vault protein Cytological Location  16p11.2
Brief Description  major vault protein
Description  This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
  • synonyms:
  • X79882,
  • VAULT1,
  • OTTHUMG00000048227,
  • VAULT1,
  • LRP,
  • NM_005115,
  • MVP,
  • uc002duj.3,
  • lung resistance-related protein,
  • HGNC:7531,
  • LRP
  • identifiers:
  • 9961,
  • ENSG00000013364,
  • MVP

Genome feature

Region: gene ? Length: 27646  
Location: 16:29820394-29848039 Cyto location: 16p11.2


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

636 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results