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Gene : DSG2 Homo sapiens

Name  ? desmoglein 2 Cytological Location  18q12.1
Brief Description  desmoglein 2
Description  This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]
  • synonyms:
  • NM_001943,
  • DSG2,
  • HDGC,
  • OTTHUMG00000179649,
  • uc002kwu.5,
  • HGNC:3049,
  • CDHF5,
  • CDHF5,
  • Z26317
  • identifiers:
  • 1829,
  • ENSG00000046604,
  • DSG2

Genome feature

Region: gene ? Length: 50832  
Location: 18:31498177-31549008 Cyto location: 18q12.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



726 SN Ps

5 Cross References

20 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results