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Gene : SPAG4 Homo sapiens

Name  ? sperm associated antigen 4 Cytological Location  20q11.22
Brief Description  sperm associated antigen 4
Description  The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
  • synonyms:
  • AF043344,
  • CT127,
  • NM_003116,
  • CT127,
  • SPAG4,
  • uc002xdb.2,
  • Sad1 and UNC84 domain containing 4,
  • acrosomal protein ACR55,
  • SUN4,
  • OTTHUMG00000032352,
  • HGNC:11214,
  • SUN4,
  • cancer/testis antigen 127
  • identifiers:
  • 6676,
  • ENSG00000061656,
  • SPAG4

Genome feature

Region: gene ? Length: 5266  
Location: 20:35615829-35621094 Cyto location: 20q11.22

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results