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Gene : VMP1 Homo sapiens

Name  ? vacuole membrane protein 1 Cytological Location  17q23.1
Brief Description  vacuole membrane protein 1
Description  This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016]
  • synonyms:
  • EPG3,
  • EPG3,
  • TANGO5,
  • ectopic P-granules autophagy protein 3 homolog (C. elegans),
  • NM_030938,
  • transport and golgi organization 5 homolog (Drosophila),
  • transmembrane protein 49,
  • TMEM49,
  • TMEM49,
  • OTTHUMG00000179882,
  • VMP1,
  • HGNC:29559,
  • TANGO5,
  • uc002ixu.5
  • identifiers:
  • 81671,
  • ENSG00000062716,
  • VMP1

Genome feature

Region: gene ? Length: 134602  
Location: 17:59707654-59842255 Cyto location: 17q23.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

272 SN Ps

5 Cross References

17 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results