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Gene : MNT Homo sapiens

Name  ? MAX network transcriptional repressor Cytological Location  17p13.3
Brief Description  MAX network transcriptional repressor
Description  The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MXD6,
  • Y13444,
  • bHLHd3,
  • OTTHUMG00000090603,
  • MNT,
  • Max-interacting protein,
  • HGNC:7188,
  • uc002fur.4,
  • NM_020310,
  • myc antagonist,
  • ROX,
  • MXD6,
  • MAD6,
  • ROX,
  • MAX binding protein,
  • bHLHd3,
  • MAD6,
  • MNT, MAX dimerization protein
  • identifiers:
  • 4335,
  • ENSG00000070444,
  • MNT

Genome feature

Region: gene ? Length: 16988  
Location: 17:2384073-2401060 reverse strand Cyto location: 17p13.3


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0 Pathways

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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SNPs

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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

0 Pathways

540 SN Ps

5 Cross References

15 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results