help  | about  | cite  | software

Gene : MNT Homo sapiens

Name  ? MAX network transcriptional repressor Cytological Location  17p13.3
Brief Description  MAX network transcriptional repressor
Description  The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MXD6,
  • Y13444,
  • bHLHd3,
  • OTTHUMG00000090603,
  • MNT,
  • Max-interacting protein,
  • HGNC:7188,
  • uc002fur.4,
  • NM_020310,
  • myc antagonist,
  • ROX,
  • MXD6,
  • MAD6,
  • ROX,
  • MAX binding protein,
  • bHLHd3,
  • MAD6,
  • MNT, MAX dimerization protein
  • identifiers:
  • 4335,
  • ENSG00000070444,
  • MNT

Genome feature

Region: gene ? Length: 16988  
Location: 17:2384073-2401060 reverse strand Cyto location: 17p13.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

540 SN Ps

5 Cross References

15 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results