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Gene : STK10 Homo sapiens

Name  ? serine/threonine kinase 10 Cytological Location  5q35.1
Brief Description  serine/threonine kinase 10
Description  This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:11388,
  • NM_005990,
  • lymphocyte-oriented kinase,
  • LOK,
  • PRO2729,
  • OTTHUMG00000163265,
  • LOK,
  • STK10,
  • PRO2729,
  • AB015718,
  • uc003mbo.2
  • identifiers:
  • 6793,
  • ENSG00000072786,
  • STK10

Genome feature

Region: gene ? Length: 146151  
Location: 5:172042074-172188224 reverse strand Cyto location: 5q35.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

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Other

520 SN Ps

5 Cross References

16 Data Sets

49 Homologues

0 Located Features

97 Rna Seq Results