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Gene : SEMA3A Homo sapiens

Name  ? semaphorin 3A Cytological Location  7q21.11
Brief Description  semaphorin 3A
Description  This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
  • synonyms:
  • COLL1,
  • HH16,
  • SEMA3A,
  • HGNC:10723,
  • coll-1,
  • SEMA1,
  • NM_006080,
  • uc003uhz.4,
  • SEMA1,
  • SemD,
  • SemD,
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A,
  • L26081,
  • SEMAD,
  • Hsema-I,
  • coll-1,
  • SEMAL,
  • OTTHUMG00000023443,
  • sema III,
  • SEMAD,
  • Hsema-I,
  • Hsema-III
  • identifiers:
  • 10371,
  • ENSG00000075213,
  • SEMA3A

Genome feature

Region: gene ? Length: 559413  
Location: 7:83955777-84515189 reverse strand Cyto location: 7q21.11

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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3756 SN Ps

5 Cross References

19 Data Sets

31 Homologues

0 Located Features

97 Rna Seq Results