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Gene : SART3 Homo sapiens

Name  ? spliceosome associated factor 3, U4/U6 recycling protein Cytological Location  12q23.3
Brief Description  spliceosome associated factor 3, U4/U6 recycling protein
Description  The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000169449,
  • TIP110,
  • PRP24 homolog,
  • squamous cell carcinoma antigen recognized by T cells 3,
  • AB020880,
  • DSAP1,
  • SART3,
  • RP11-13G14,
  • KIAA0156,
  • RP11-13G14,
  • uc001tmz.2,
  • NM_014706,
  • p110,
  • p110(nrb),
  • TIP110,
  • p110,
  • HGNC:16860,
  • squamous cell carcinoma antigen recognized by T-cells 3,
  • HIV-1 Tat-interacting protein of 110kDa,
  • P100
  • identifiers:
  • 9733,
  • ENSG00000075856,
  • SART3

Genome feature

Region: gene ? Length: 38960  
Location: 12:108522214-108561173 reverse strand Cyto location: 12q23.3


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

212 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results