help  | about  | cite  | software

Gene : KAT6A Homo sapiens

Name  ? lysine acetyltransferase 6A Cytological Location  8p11.21
Brief Description  lysine acetyltransferase 6A
Description  This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
  • synonyms:
  • HGNC:13013,
  • MRD32,
  • MYST3,
  • ZNF220,
  • OTTHUMG00000150453,
  • ZNF220,
  • ZC2HC6A,
  • MYST histone acetyltransferase (monocytic leukemia) 3,
  • Monocytic leukemia zinc finger protein,
  • MYST3,
  • MOZ,
  • RUNXBP2,
  • RUNXBP2,
  • uc010lxc.3,
  • MYST-3,
  • NM_006766,
  • MOZ,
  • K(lysine) acetyltransferase 6A,
  • U47742,
  • ZC2HC6A,
  • runt-related transcription factor binding protein 2,
  • KAT6A
  • identifiers:
  • 7994,
  • ENSG00000083168,
  • KAT6A

Genome feature

Region: gene ? Length: 122510  
Location: 8:41929479-42051988 reverse strand Cyto location: 8p11.21


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

369 SN Ps

5 Cross References

18 Data Sets

16 Homologues

0 Located Features

97 Rna Seq Results