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Gene : TREM2 Homo sapiens

Name  ? triggering receptor expressed on myeloid cells 2 Cytological Location  6p21.1
Brief Description  triggering receptor expressed on myeloid cells 2
Description  This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
  • synonyms:
  • NM_018965,
  • uc003opy.4,
  • Trem2b,
  • AF213457,
  • PLOSL2,
  • triggering receptor expressed on myeloid cells 2a,
  • TREM2,
  • TREM-2,
  • Trem2c,
  • Trem2c,
  • HGNC:17761,
  • OTTHUMG00000014671,
  • Trem2b,
  • Trem2a,
  • Trem2a,
  • TREM-2
  • identifiers:
  • 54209,
  • ENSG00000095970,
  • TREM2

Genome feature

Region: gene ? Length: 4609  
Location: 6:41158508-41163116 reverse strand Cyto location: 6p21.1


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Disease

1 Diseases

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162 SN Ps

5 Cross References

19 Data Sets

26 Homologues

0 Located Features

97 Rna Seq Results