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Gene : MFNG Homo sapiens

Name  ? MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Cytological Location  22q13.1
Brief Description  MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Description  This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the LFNG (GeneID: 3955) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]
  • synonyms:
  • manic fringe homolog (Drosophila),
  • MFNG,
  • HGNC:7038,
  • uc003ass.3,
  • OTTHUMG00000150560,
  • manic fringe (Drosophila) homolog,
  • BC094814,
  • NM_002405
  • identifiers:
  • 4242,
  • ENSG00000100060,
  • MFNG

Genome feature

Region: gene ? Length: 17325  
Location: 22:37469063-37486387 reverse strand Cyto location: 22q13.1

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0 Diseases

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145 SN Ps

4 Cross References

14 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results