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Gene : SNW1 Homo sapiens

Name  ? SNW domain containing 1 Cytological Location  14q24.3
Brief Description  SNW domain containing 1
Description  This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
  • synonyms:
  • SKIP,
  • NM_012245,
  • FUN20,
  • SKIIP,
  • SNW1,
  • SKIP1,
  • PRPF45,
  • Prp45,
  • AF045184,
  • SKIIP,
  • uc001xuf.4,
  • SKI interacting protein,
  • SKIP,
  • OTTHUMG00000171527,
  • Prp45,
  • NCOA-62,
  • Bx42,
  • NCoA-62,
  • Bx42,
  • HGNC:16696,
  • SKIP1,
  • PRPF45,
  • FUN20
  • identifiers:
  • 22938,
  • ENSG00000100603,
  • SNW1

Genome feature

Region: gene ? Length: 43558  
Location: 14:77717599-77761156 reverse strand Cyto location: 14q24.3

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0 Diseases

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3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results