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Gene : ARHGEF18 Homo sapiens

Name  ? Rho/Rac guanine nucleotide exchange factor 18 Cytological Location  19p13.2
Brief Description  Rho/Rac guanine nucleotide exchange factor 18
Description  Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2018]
  • synonyms:
  • OTTHUMG00000177342,
  • MGC15913,
  • ARHGEF18,
  • AK074372,
  • P114-RhoGEF,
  • HGNC:17090,
  • KIAA0521,
  • p114RhoGEF,
  • Rho-specific guanine nucleotide exchange factor p114,
  • NM_015318,
  • rho/rac guanine nucleotide exchange factor (GEF) 18,
  • p114RhoGEF,
  • SA-RhoGEF,
  • RP78,
  • uc002mgh.4,
  • Rho/Rac guanine nucleotide exchange factor (GEF) 18,
  • P114-RhoGEF
  • identifiers:
  • 23370,
  • ENSG00000104880,
  • ARHGEF18

Genome feature

Region: gene ? Length: 128090  
Location: 19:7348901-7476990 Cyto location: 19p13.2

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1 Diseases

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576 SN Ps

6 Cross References

18 Data Sets

9 Homologues

0 Located Features

140 Rna Seq Results