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Gene : SORCS1 Homo sapiens

Name  ? sortilin related VPS10 domain containing receptor 1 Cytological Location  10q25.1
Brief Description  sortilin related VPS10 domain containing receptor 1
Description  This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • synonyms:
  • sorCS1,
  • OTTHUMG00000019018,
  • HGNC:16697,
  • hSorCS,
  • SORCS1,
  • AF284756,
  • uc001kym.4,
  • sortilin-related VPS10 domain containing receptor 1,
  • NM_052918
  • identifiers:
  • 114815,
  • ENSG00000108018,
  • SORCS1

Genome feature

Region: gene ? Length: 607476  
Location: 10:106573663-107181138 reverse strand Cyto location: 10q25.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

883 SN Ps

5 Cross References

15 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results