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Gene : ST8SIA1 Homo sapiens

Name  ? ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Cytological Location  12p12.1
Brief Description  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Description  Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
  • synonyms:
  • SIAT8,
  • SIAT8,
  • ST8SIA1,
  • L32867,
  • SIAT8A,
  • GD3S,
  • uc001rfo.4,
  • OTTHUMG00000169098,
  • sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A,
  • SIAT8A,
  • NM_003034,
  • ST8SiaI,
  • SIAT8-A,
  • ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1,
  • ST8Sia I,
  • HGNC:10869
  • identifiers:
  • 6489,
  • ENSG00000111728,
  • ST8SIA1

Genome feature

Region: gene ? Length: 141324  
Location: 12:22193391-22334714 reverse strand Cyto location: 12p12.1

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0 Diseases

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3756 SN Ps

5 Cross References

17 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results