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Gene : PPARD Homo sapiens

Name  ? peroxisome proliferator activated receptor delta Cytological Location  6p21.31
Brief Description  peroxisome proliferator activated receptor delta
description  This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]
  • synonyms:
  • peroxisome proliferator-activated receptor delta,
  • PPARD,
  • NR1C2,
  • NUCII,
  • NR1C2,
  • FAAR,
  • PPARB,
  • NUCII,
  • OTTHUMG00000014567,
  • L07592,
  • HGNC:9235,
  • peroxisome proliferative activated receptor, delta,
  • uc003okm.3,
  • NUCI,
  • NUC1,
  • NUC1,
  • FAAR,
  • NM_006238
  • identifiers:
  • 5467,
  • ENSG00000112033,

Genome feature

Region: gene ? Length: 85634  
Location: 6:35342558-35428191 Cyto location: 6p21.31

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794 SN Ps

5 Cross References

17 Data Sets

22 Homologues

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97 Rna Seq Results