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Gene : PRLR Homo sapiens

Name  ? prolactin receptor Cytological Location  5p13.2
Brief Description  prolactin receptor
Description  This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
  • synonyms:
  • RI-PRLR,
  • PRLR,
  • hPRLrI,
  • uc032uqm.2,
  • NM_000949,
  • OTTHUMG00000090789,
  • MFAB,
  • HPRL,
  • HGNC:9446
  • identifiers:
  • 5618,
  • ENSG00000113494,
  • PRLR

Genome feature

Region: gene ? Length: 181969  
Location: 5:35048756-35230724 reverse strand Cyto location: 5p13.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

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Other

3756 SN Ps

5 Cross References

19 Data Sets

29 Homologues

0 Located Features

97 Rna Seq Results