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Gene : IL4 Homo sapiens

Name  ? interleukin 4 Cytological Location  5q31.1
Brief Description  interleukin 4
description  The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • synonyms:
  • IL4,
  • IL-4,
  • uc003kxk.3,
  • BCGF-1,
  • MGC79402,
  • OTTHUMG00000059724,
  • B_cell stimulatory factor 1,
  • B cell growth factor 1,
  • BCGF1,
  • BSF-1,
  • BSF1,
  • NM_000589,
  • IL-4,
  • M23442,
  • lymphocyte stimulatory factor 1,
  • HGNC:6014,
  • BCGF1,
  • BSF1,
  • BCGF-1
  • identifiers:
  • 3565,
  • ENSG00000113520,
  • IL4

Genome feature

Region: gene ? Length: 8693  
Location: 5:132673986-132682678 Cyto location: 5q31.1

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0 Diseases

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551 SN Ps

5 Cross References

16 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results