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Gene : GRB14 Homo sapiens

Name  ? growth factor receptor bound protein 14 Cytological Location  2q24.3
Brief Description  growth factor receptor bound protein 14
Description  The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  • synonyms:
  • uc002ucl.4,
  • growth factor receptor-bound protein 14,
  • OTTHUMG00000132135,
  • HGNC:4565,
  • GRB14,
  • NM_004490
  • identifiers:
  • 2888,
  • ENSG00000115290,
  • GRB14

Genome feature

Region: gene ? Length: 130543  
Location: 2:164492417-164622959 reverse strand Cyto location: 2q24.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

646 SN Ps

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results