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Gene : ST3GAL5 Homo sapiens

Name  ? ST3 beta-galactoside alpha-2,3-sialyltransferase 5 Cytological Location  2p11.2
Brief Description  ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Description  Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ST3GAL5,
  • SIATGM3S,
  • HGNC:10872,
  • ST3Gal V,
  • uc002sqq.2,
  • SATI,
  • ST3GalV,
  • ST3GalV,
  • SIATGM3S,
  • SIAT9,
  • OTTHUMG00000130171,
  • NM_003896,
  • AB018356,
  • SIAT9,
  • sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase),
  • SPDRS
  • identifiers:
  • 8869,
  • ENSG00000115525,
  • ST3GAL5

Genome feature

Region: gene ? Length: 51915  
Location: 2:85837120-85889034 reverse strand Cyto location: 2p11.2


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Disease

1 Diseases

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3756 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results