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Gene : SCP2 Homo sapiens

Name  ? sterol carrier protein 2 Cytological Location  1p32.3
Brief Description  sterol carrier protein 2
Description  This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]
  • synonyms:
  • SCP-CHI,
  • SCP-X,
  • NLTP,
  • SCP2,
  • NM_002979,
  • SCPX,
  • SCP-2,
  • HGNC:10606,
  • uc001cur.3,
  • NSL-TP,
  • OTTHUMG00000008936,
  • M75884
  • identifiers:
  • 6342,
  • ENSG00000116171,
  • SCP2

Genome feature

Region: gene ? Length: 124470  
Location: 1:52927229-53051698 Cyto location: 1p32.3


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Disease

1 Diseases

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3756 SN Ps

5 Cross References

19 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results