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Gene : MMP8 Homo sapiens

Name  ? matrix metallopeptidase 8 Cytological Location  11q22.2
Brief Description  matrix metallopeptidase 8
description  This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  • synonyms:
  • HGNC:7175,
  • CLG1,
  • MMP-8,
  • MMP8,
  • NM_002424,
  • PMNL-CL,
  • OTTHUMG00000167587,
  • uc001phe.2,
  • CLG1,
  • HNC,
  • matrix metalloproteinase 8 (neutrophil collagenase),
  • J05556
  • identifiers:
  • 4317,
  • ENSG00000118113,
  • MMP8

Genome feature

Region: gene ? Length: 13172  
Location: 11:102711796-102724967 reverse strand Cyto location: 11q22.2

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

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Gene --> GO terms.



34 SN Ps

5 Cross References

16 Data Sets

32 Homologues

0 Located Features

97 Rna Seq Results