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Gene : MT2A Homo sapiens

Name  ? metallothionein 2A Cytological Location  16q13
Brief Description  metallothionein 2A
Description  This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]
  • synonyms:
  • MT2,
  • MT-2,
  • MT2A,
  • MT2,
  • HGNC:7406,
  • BC007034,
  • MT-II,
  • OTTHUMG00000133281,
  • uc002ejh.4,
  • NM_005953
  • identifiers:
  • 4502,
  • ENSG00000125148,
  • MT2A

Genome feature

Region: gene ? Length: 914  
Location: 16:56608584-56609497 Cyto location: 16q13

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Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



54 SN Ps

5 Cross References

15 Data Sets

14 Homologues

0 Located Features

97 Rna Seq Results