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Gene : TNFSF14 Homo sapiens

Name  ? TNF superfamily member 14 Cytological Location  19p13.3
Brief Description  TNF superfamily member 14
Description  The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • synonyms:
  • TNFSF14,
  • NM_001376887,
  • uc002mfk.3,
  • tumor necrosis factor (ligand) superfamily, member 14,
  • LIGHT,
  • OTTHUMG00000181835,
  • HGNC:11930,
  • HVEML,
  • AF036581,
  • CD258,
  • CD258,
  • LIGHT,
  • LTg,
  • LTg,
  • HVEM-L
  • identifiers:
  • 8740,
  • ENSG00000125735,
  • TNFSF14

Genome feature

Region: gene ? Length: 12470  
Location: 19:6658126-6670595 reverse strand Cyto location: 19p13.3

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0 Diseases

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35 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results