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Gene : ILF3 Homo sapiens

Name  ? interleukin enhancer binding factor 3 Cytological Location  19p13.2
Brief Description  interleukin enhancer binding factor 3
Description  This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]
  • synonyms:
  • NF110,
  • MPP4110,
  • double-stranded RNA-binding protein, 76 kD,
  • NFAR-2,
  • NF110,
  • MPHOSPH4,
  • NF90c,
  • NFAR-1,
  • NF90ctv,
  • nuclear factor of activated T-cells 110 kDa,
  • NFAR-1,
  • OTTHUMG00000180587,
  • DRBP76,
  • MMP4,
  • NFAR90,
  • NF90ctv,
  • NF90a,
  • NFAR,
  • MPHOSPH4,
  • dsRNA binding protein NFAR-2/MPP4,
  • TCP80,
  • TCP110,
  • MPP4,
  • MPP4110,
  • MPP4,
  • translational control protein 80,
  • NF90b,
  • M phase phosphoprotein 4, nuclear factor associated with DS RNA,
  • CBTF,
  • NM_001137673,
  • interleukin enhancer binding factor 3, 90kDa,
  • DRBP76,
  • NF110b,
  • DRBF,
  • NFAR110,
  • NF110b,
  • NF90,
  • nuclear factor of activated T-cells 90 kDa,
  • NFAR90,
  • M-phase phosphoprotein 4,
  • NF90a,
  • NFAR110,
  • NF90c,
  • TCP110,
  • NF-AT-90,
  • NFAR2,
  • ILF3,
  • NFAR-2,
  • U10324,
  • NF90,
  • uc002mpo.4,
  • HGNC:6038,
  • interleukin enhancer binding factor 3, 90kD
  • identifiers:
  • 3609,
  • ENSG00000129351,
  • ILF3

Genome feature

Region: gene ? Length: 38159  
Location: 19:10654261-10692419 Cyto location: 19p13.2


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149 SN Ps

5 Cross References

16 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results