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Gene : LBP Homo sapiens

Name  ? lipopolysaccharide binding protein Cytological Location  20q11.23
Brief Description  lipopolysaccharide binding protein
Description  The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
  • synonyms:
  • LBP,
  • lipopolysaccharide-binding protein,
  • OTTHUMG00000032447,
  • BPI fold containing family D, member 2,
  • uc002xic.3,
  • BPIFD2,
  • HGNC:6517,
  • NM_004139,
  • BPIFD2
  • identifiers:
  • 3929,
  • ENSG00000129988,
  • LBP

Genome feature

Region: gene ? Length: 30532  
Location: 20:38346482-38377013 Cyto location: 20q11.23

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0 Diseases

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219 SN Ps

5 Cross References

18 Data Sets

16 Homologues

0 Located Features

97 Rna Seq Results