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Gene : PIAS3 Homo sapiens

Name  ? protein inhibitor of activated STAT 3 Cytological Location  1q21.1
Brief Description  protein inhibitor of activated STAT 3
Description  This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_006099,
  • OTTHUMG00000013750,
  • AB021868,
  • ZMIZ5,
  • uc001eoc.2,
  • FLJ14651,
  • HGNC:16861,
  • ZMIZ5,
  • PIAS3,
  • zinc finger, MIZ-type containing 5
  • identifiers:
  • 10401,
  • ENSG00000131788,
  • PIAS3

Genome feature

Region: gene ? Length: 10560  
Location: 1:145848522-145859081 reverse strand Cyto location: 1q21.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3756 SN Ps

5 Cross References

16 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results