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Gene : FBXO21 Homo sapiens

Name  ? F-box protein 21 Cytological Location  12q24.22
Brief Description  F-box protein 21
Description  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
  • synonyms:
  • FBX21,
  • AB020682,
  • HGNC:13592,
  • F-box only protein 21,
  • FBX21,
  • OTTHUMG00000169495,
  • uc001twk.4,
  • KIAA0875,
  • FBXO21,
  • NM_033624
  • identifiers:
  • 23014,
  • ENSG00000135108,
  • FBXO21

Genome feature

Region: gene ? Length: 48481  
Location: 12:117141991-117190471 reverse strand Cyto location: 12q24.22

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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3753 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results